Basic Information
VIS ID
TVIS10007089
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2005
End
2058
Orient
-
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
92531878/91519650 (Hg38)
End
92531878/91519650 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/314091; hsa-mir-10400/Downstream/1510101;
Nearest TSS
ENST00000518652/Upstream/162402; ENST00000522980/Downstream/387803;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/448893, chr8-CpG: 151/Downstream/582178
Upstream sequence
gaaacttatttgcgatatgtgtcctcaactaacggacttgaacctttcgtttcatgcagtacctctggaacactctttttgaagattctgcatgtggata
Downstream sequence
AATAAAGACATGAAAACAGACTTTTACAGTTTGAAGTCTCTAGCCAATCCTTATTTTAATGTAGCAATTCGCAGTGTATTCTGTAATATGAAACATTAAA
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate