Basic Information
VIS ID
TVIS10007094
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1455
End
1715
Orient
-
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
96196712/95184484 (Hg38)
End
96196712/95184484 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA8B
Nearest miRNA
hsa-mir-12123/Upstream/111488; hsa-mir-10400/Downstream/3209161;
Nearest TSS
ENST00000518652/Upstream/50408; ENST00000517655/Downstream/19972;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/49983, chr8-CpG: 74/Downstream/84132
Upstream sequence
cgttggaaacaggatgcaatataaaacttacacagcagcatactcagaaaatactttgccatatttccattcaagtcacagagtggaacattcccattca
Downstream sequence
AATATCGTGCCTCATTTCCCCTTCCTAGTGATAACTGCTAATATATTTCTATGGAGCCTCTTTTAATGGTATGTATTTCAAACATTTTGTTATAAACATA
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate