Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007095
Fusion event
HBV-DHCR24 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
958
End
1251
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
p32.3
Reference genome
Start
End
55317630/54851957 (Hg38)
Orient
+
Location type
Exon
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-335-5p ; hsa-mir-155-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-24-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-1299 ; hsa-mir-642a-5p ; hsa-mir-5093 ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-191-5p ; hsa-mir-4694-3p ; hsa-mir-7156-3p ; hsa-mir-205-5p ; hsa-mir-510-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-488-3p ; hsa-mir-4753-3p ; hsa-mir-3911 ; hsa-mir-130b-5p ; hsa-mir-4496 ; hsa-mir-595 ; hsa-mir-100-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-711 ; hsa-mir-7114-3p ; hsa-mir-1180-5p ; hsa-mir-532-3p ; hsa-mir-1224-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-4796-3p
Nearest miRNA
hsa-mir-12136/Upstream/797803; hsa-mir-101-1/Downstream/373684;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/45658, chr1-CpG: 107/Downstream/34833
Upstream sequence
accacttacccagcaccttcaatgtgaccagtgctcaactcagatgacaacaacctgcaagtaggtattactatccctttcaactaatgaagagacccgg
Downstream sequence
gctcagaggggttaagggactcacccagagtcacacagctaatgagttctaaacggggaactggactcaggcttgtctgactccaaatcccacattcttt
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.