Basic Information
VIS ID
TVIS10007101
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2693
End
2905
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
26231467/26231358 (Hg38)
End
26231467/26231358 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA5E
Nearest miRNA
hsa-mir-10397/Upstream/9075366; hsa-mir-103a-1/Downstream/5704744;
Nearest TSS
ENST00000502646/Upstream/785433; ENST00000514255/Downstream/168461;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/321816, chr5-CpG: 28/Downstream/438081
Upstream sequence
AGCCAGGGTGCTGGGGCTGCGGGTGGGGAAAGGAGGCCCCAGCACTTCAGACAAAGACCACCCCTTCACCCACTGGACCCCAAGCCGCAAAAGCTGGGGA
Downstream sequence
attctcctgccttagcctcctgagtacctgcgactacaggcatgtgccaccacacccggctacaccttgatctcagagacttctggcccccagaaccgtg
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
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