Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007103
Fusion event
HBV-MTRNR2L1 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
1986
End
2103
Orient
+
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
Start
End
22022861/22523535 (Hg38)
Orient
-
Location type
Exon
Target gene
miRNAs that regulate target gene
hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-640 ; hsa-mir-3151-3p ; hsa-mir-219b-5p ; hsa-mir-5187-5p ; hsa-mir-6513-5p ; hsa-mir-6728-5p ; hsa-mir-4539 ; hsa-mir-378j ; hsa-mir-6839-5p ; hsa-mir-541-5p ; hsa-mir-376c-3p ; hsa-mir-127-5p ; hsa-mir-382-5p ; hsa-mir-4680-5p ; hsa-mir-619-3p ; hsa-mir-490-3p ; hsa-mir-5100 ; hsa-mir-3117-3p ; hsa-mir-633 ; hsa-mir-4330 ; hsa-mir-1288-5p ; hsa-mir-8083 ; hsa-mir-3169 ; hsa-mir-4759 ; hsa-mir-5089-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-767-5p ; hsa-mir-3130-3p ; hsa-mir-431-3p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-642a-5p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-28-3p ; hsa-mir-1296-5p ; hsa-mir-155-5p ; hsa-mir-2861 ; hsa-mir-2909 ; hsa-mir-3912-3p ; hsa-mir-4490 ; hsa-mir-4512 ; hsa-mir-4774-5p ; hsa-mir-569 ; hsa-mir-6895-5p ; hsa-mir-7160-3p
Nearest miRNA
hsa-mir-1180/Upstream/3178961; hsa-mir-10226/Downstream/4770375;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/5672, chr17-CpG: 22/Downstream/29040
Upstream sequence
GGTGATAGCTGGTTGTCCAAGATAGAATCTTAGTTCAACTTTAAATTTATCTACAGAACCAGCTAATGCCTTTGTAAATTTAACTGTTAGTCTAAAGAGG
Downstream sequence
GACAGCTCTTTAGACACTAGGAAAAAACCTTGTAGAGAGAGTAAAAAATATAACTTCCAAAGTTGGCCTAGAAGAAGCGATCAATTAAGAAGGCGTTCAA
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.