Basic Information
VIS ID
TVIS10007104
Fusion event
HBV-CFAP221 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2989
End
31
Orient
-
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
120397926/119640350 (Hg38)
End
120397926/119640350 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
FRA2S
Target gene
CFAP221
Nearest miRNA
hsa-mir-1285-2/Upstream/5918982; hsa-mir-10b/Downstream/7783187;
Nearest TSS
ENST00000437798/Upstream/1988; ENST00000464578/Downstream/15615;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/95471, chr2-CpG: 52/Downstream/38604
Upstream sequence
GATTAGCCTTCCGCAGTCTCTGTATCCAGTTCCAAAGGATCCATGGCCCTCTTGTGCCACAGGCTGGCATTCACTGTGAGACCATGGCAATCCCCACACA
Downstream sequence
GAAAACAGCCCTGCTCCAGATACACAATGGGTAGATCAGAATATTGTTGGATGATGAAAGAAGAAACTTAGAGTGACTACATTTTTGCTAATTTGCTTAT
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate