Basic Information
VIS ID
TVIS10007106
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2634
End
2887
Orient
-
Host Sequence
Chromosome
chr8
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
73179518/72267283 (Hg38)
End
73179518/72267283 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/7888026; hsa-mir-10400/Downstream/2281260;
Nearest TSS
ENST00000518652/Upstream/70949; ENST00000521224/Downstream/195028;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/15327, chr8-CpG: 112/Downstream/269141
Upstream sequence
tcgttggaaacgggatgaatatcaaacgtacacagcagcatactcagaaaatactttgccatatttccattcaagtcacagagtggaacattcccattca
Downstream sequence
tcctttcccaagtgaaaagcttggtttaggatcttaaggaatttccactgcttggaggcaggcaagtggagcttgccatcctatgactgtagacatccag
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate