Basic Information
VIS ID
TVIS10007108
Fusion event
HBV-LOC107986562 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2084
End
2196
Orient
+
Host Sequence
Chromosome
chr6
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
9136966/9136733 (Hg38)
End
9136966/9136733 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986562
Nearest miRNA
hsa-mir-3691/Upstream/2967298; hsa-mir-10398/Downstream/1302984;
Nearest TSS
ENST00000381078/Upstream/701122; ENST00000645232/Downstream/25044;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/700825, chr6-CpG: 41/Downstream/262127
Upstream sequence
tggcagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatgaa
Downstream sequence
GTTGTTTGCATATCTATTTTTCATAAAAACCACAGACATTTTGATGTGTATGCCTTGAATTAATGCAGAAACCAATGGCCTACATGTGAAGACACCAGCT
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate