Basic Information
VIS ID
TVIS10007110
Fusion event
HBV-chr17 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26553052
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Not given
Start
2944
End
3020
Orient
+
Host Sequence
Chromosome
chr17
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
22245465/22746138 (Hg38)
End
22245465/22746138 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/3401564; hsa-mir-10226/Downstream/4547772;
Nearest TSS
ENST00000595228/Upstream/53304; ENST00000583786/Downstream/4253787;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/53456, chr17-CpG: 114/Downstream/3984890
Upstream sequence
aactagagggaagcattgtcagaaacttgtttgtgatgactgcattcaactcacagagttgaaggttccttttcaaacagcagtttccaaacactctttc
Downstream sequence
tgtggcatctgcaagtggatgattgggcctctttgaagatttcgttggaaacgggataatcttcacagaaaagctaaacagaagcattctcagaaacttc
Reference
Kawai-Kitahata, F., et al. Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features. J Gastroenterol ,2016,51(5): 473-486.
Curate