VISDB Viral Integration Site DataBase

VIS ID

TVIS10007111

Fusion event

HBV-PSMD4 integration

Validated

Yes

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1946

Orient

+

Integrated sequence

CTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTT| |ACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGT

Chromosome

chr1

Cytoband

q21.3

Reference genome

Start

End

151238731/151266255 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-744-5p ; hsa-mir-324-5p ; hsa-mir-186-5p ; hsa-mir-221-3p ; hsa-mir-93-5p

Nearest miRNA

hsa-mir-101-1/Upstream/714241; hsa-mir-1182/Downstream/279541;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/67199, chr1-CpG: 153/Downstream/14927

Upstream sequence

AACATTGAAAGCTGGGTGTAGGCACTGCAGGGAGAGTGTGGAGGTCTGACAGGGTAGGAATATGTGGGAGGGCTGGGCTAGGAATGGCCTTGGAGGCTGG

Downstream sequence

CCTGTGTGGATATGGCACCAATTCTACCCTGCTCCTCTTTTCCTTTTCCCAGACTCAGACGATGCCCTGCTGAAGATGACCATCAGCCAGCAAGAGTTTG