Basic Information
VIS ID
TVIS10007112
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
990
Orient
+
Integrated sequence
ATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTAT| |GTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGC
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
End
152118655/152146179 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/600288; hsa-mir-1182/Downstream/1543526;
Nearby gene
TCHH(-32099) ; RPTN(+7416) ;
Upstream sequence
ATTAGAGAAGATAAGTTTTAAATTGGCCTTTCAAGGAGTTGATGGTTAGGAATTGTTGGGTTTGAACTCCAAGGGAGAAGAAGAAGTAAGGAAGTGTCTA
Downstream sequence
AGGAGTGAGAAAATAGAATGGTCACAACCTGGGATCCTACAATTCAGGGAGGGCATTGGTGGTGCTGAGGGGAACCTAGCTACCATTTAGGGGTGTTTAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate