VISDB Viral Integration Site DataBase

VIS ID

TVIS10007126

Fusion event

HBV-C12orf4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1388

Orient

+

Integrated sequence

CGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGC| |TGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTC

Chromosome

chr12

Cytoband

p13.32

Reference genome

Start

End

4622485/4513319 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-196a-5p ; hsa-let-7d-5p ; hsa-mir-1261 ; hsa-mir-4635 ; hsa-mir-526b-5p ; hsa-mir-4503 ; hsa-mir-877-5p ; hsa-mir-6792-5p ; hsa-mir-4696 ; hsa-mir-4451 ; hsa-mir-4500 ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4790-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125

Nearest miRNA

hsa-mir-3649/Upstream/2852939; hsa-let-7i/Downstream/2450380;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/67861, chr12-CpG: 20/Downstream/25359

Upstream sequence

cactgctcaaggaaataaaagaggatacaaacaaatggaagaacattccatgctcatgggtaggaagaatcaatatcgtgaaaatggccatactgcccaa

Downstream sequence

ggtaatttacagattcagtgccatccgcatcacaagctaccaatgactttcttcacagaattggaaaaaactactttaaagttcatatggaaccaaaaaa