Basic Information
VIS ID
TVIS10007134
Fusion event
HBV-C13orf42 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2833
Orient
+
Integrated sequence
CCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGG| |GAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCA
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
51679879/51105743 (Hg38)
End
51679879/51105743 (Hg38)
Orient
-
Location type
Intronic
Target gene
C13orf42
Nearest miRNA
hsa-mir-15a/Upstream/1056542; hsa-mir-1267/Downstream/242824;
Nearest TSS
ENST00000623511/Upstream/157679; ENST00000614264/Downstream/5466;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/195288, chr13-CpG: 86/Downstream/116238
Nearby gene
GUCY1B2(-39586) ; FAM124A(+116591) ;
Upstream sequence
ccaaatctaaggctcatctatggcagctgaattagcttctatgatctgcatattattttgagtggtcttgattttctatgattttttttctctcctgatt
Downstream sequence
ttccaatttCTGGTGCTACTTAACAATTCTGTATGCTCTTGAATCTTGTATGTTATACAAGATCAAAATACGTTTTCCAGTCAAAAGATGCTGTAGATAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate