Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007139
Fusion event
HBV-LOC652276 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
109
Orient
+
Integrated sequence
ACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCT| |CTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGG
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
Start
End
2680058/2630057 (Hg38)
Orient
+
Location type
ncRNA_exonic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/98052; hsa-mir-11401/Downstream/855324;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/7001, chr16-CpG: 21/Downstream/4962
Upstream sequence
CCTTCCTGTTTGGTGAGTGCTGCCTCCACACCTGGCTGCATGCCAGAAAGGCCTGCACAGGTCAGAACACAGGTTTCCAAACCCTACTCCAAGTCTGAAC
Downstream sequence
CTCCAAGGACACCCCGAGCTCCCCAAGGTTCTTGCATAGAGGGCACAGGCCAGAGACAGCCCAGGTGGGAAGCTTACTCTGAGTCAGCTGCCCTCACCAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.