Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007144
Fusion event
HBV-DLGAP1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2812
Orient
+
Integrated sequence
ACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTT| |TGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCA
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
Start
End
3936770/3936770 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-6718/Upstream/51338; hsa-mir-1-2/Downstream/1903925;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/56683, chr18-CpG: 169/Downstream/517199
Upstream sequence
aagatttaaatatgatgtttgaatgaataaatGAGTGAAATGTTCTCAAAAAGCATTCTAGAAAGGTTCCTCCAGTACCTCAATATCCACAAAATGATTC
Downstream sequence
ACAATTTGGAGGCATATATGGGGTAATGTGGCAACTGTTAGCTTACCCAAGAACAAAGAAGCAGGAATGATGAACCATCACTGAGAAGCTCTAATCAGGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.