VISDB Viral Integration Site DataBase

VIS ID

TVIS10007145

Fusion event

HBV-MYH14 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1880

Orient

+

Integrated sequence

GGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCT| |GTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCA

Chromosome

chr19

Cytoband

q13.33

Reference genome

Start

End

50743508/50240251 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-412-3p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-4728-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-6760-5p ; hsa-mir-4428 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4533 ; hsa-mir-9500 ; hsa-mir-1275 ; hsa-mir-2467-3p ; hsa-mir-3127-5p ; hsa-mir-363-5p ; hsa-mir-4271 ; hsa-mir-4506 ; hsa-mir-4525 ; hsa-mir-4651 ; hsa-mir-4665-5p ; hsa-mir-4693-3p ; hsa-mir-4723-5p ; hsa-mir-4725-3p ; hsa-mir-5000-5p ; hsa-mir-5010-5p ; hsa-mir-5192 ; hsa-mir-5680 ; hsa-mir-5698 ; hsa-mir-608 ; hsa-mir-625-5p ; hsa-mir-6716-5p ; hsa-mir-6745 ; hsa-mir-6780b-5p ; hsa-mir-6782-5p ; hsa-mir-6798-5p ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-8071

Nearest miRNA

hsa-mir-10395/Upstream/307114; hsa-let-7e/Downstream/966678;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/9220, chr19-CpG: 21/Downstream/18834

Upstream sequence

tgtCCAGTGAGGGAAGGGGGCTTTGGAGAGgccagttccacagacacattcactttgtaaacgttcctggagctggatgtctatagtatgtgtccttttc

Downstream sequence

tgtatgtgtGCTGCGCATATGTATTTACATTCATAAACCTATGCTACGCCggcacggtggcttatgcctgtaatcccagcactttgggaggctgagttag