Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007147
Fusion event
HBV-DIRC3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
86
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGT| |AAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGA
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
End
218354377/217489654 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/3731495; hsa-mir-1244-1/Downstream/410859;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/679163, chr2-CpG: 23/Downstream/266902
Upstream sequence
CCCCCTACTCTTCTTTGTGAGCAACTCACTATTTGGCCGTTTGGCTCCCCGGGGGTCTCTGTGCCTCAGACCGCAGGCCTCTCTGAGAGTTGTTGATGCC
Downstream sequence
TCAGAGCGGCTGACTTGCAGATTGTATCCGTATTCCCCCAGCTCAGACCTCCCACCACCACTCAGCGGACAACTTAGGGATGCCCTCAAAGCTGCGTGCC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.