Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007151
Fusion event
HBV-COMMD1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
899
Orient
+
Integrated sequence
TGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGT| |TATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAA
Host Sequence
Chromosome
chr2
Cytoband
p15
Reference genome
Start
End
62299210/62072075 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1301/Upstream/1684630; hsa-mir-10b/Downstream/133751;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/183220, chr2-CpG: 157/Downstream/122981
Upstream sequence
taaaaaTCTTGTTAAATTGTTTTTTTttttaattaacccagtataatgtggcttattttccagcctcactctagtatagtatcacatgacaggtagtaga
Downstream sequence
ccctgaagaaaataaaaatattttactacactatatatatttatatgtatatattctTTTATGAGCCACCTCCCCATGCTGCTGATAGTGAcaggaggta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.