VISDB Viral Integration Site DataBase

VIS ID

TVIS10007156

Fusion event

HBV-chr20 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

702

Orient

+

Integrated sequence

TATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGG| |TTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGT

Chromosome

chr20

Cytoband

p11.21

Reference genome

Start

End

25276190/25295554 (Hg38)

Orient

+

Location type

Intronic

Target gene

ABHD12 ; PYGB

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-16-5p ; hsa-mir-744-5p ; hsa-mir-484 ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-20a-5p ; hsa-mir-378a-5p ; hsa-mir-3157-5p ; hsa-mir-5196-3p ; hsa-mir-4793-5p ; hsa-mir-4691-3p ; hsa-mir-3922-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-638 ; hsa-mir-4713-3p ; hsa-mir-661 ; hsa-mir-6778-3p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-1205 ; hsa-mir-4485-5p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-1247-3p ; hsa-mir-302a-5p ; hsa-mir-3177-5p ; hsa-mir-320a ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-4264 ; hsa-mir-4429 ; hsa-mir-4521 ; hsa-mir-4532 ; hsa-mir-4706 ; hsa-mir-4753-5p ; hsa-mir-488-3p ; hsa-mir-519a-3p ; hsa-mir-519b-3p ; hsa-mir-519c-3p ; hsa-mir-552-3p ; hsa-mir-5681a ; hsa-mir-5692a ; hsa-mir-622 ; hsa-mir-6730-5p ; hsa-mir-6800-5p ; hsa-mir-6802-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-9-3p

Nearest miRNA

hsa-mir-103a-2/Upstream/6824863; hsa-mir-1-1/Downstream/912632;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/46788, chr20-CpG: 141/Downstream/94145

Upstream sequence

TGGCTCTGACCAGCTGCGTGGGTGGGCCCCTTCGCTCCAGACAGGACCAGGTGGATGGTGCCTGGCCTCCTGCCCTGGGACTCTCCCCTCGGGACAGTGT

Downstream sequence

GGGCAGGGCTCCCTGCTGCCCTGGCCCAGCCTCCTTTCTCCCATTCCAGGTTCAAGGTGTTTGCAGACTATGAAGCCTACATGCAGTGCCAGGCACAGGT