VISDB Viral Integration Site DataBase

VIS ID

TVIS10007161

Fusion event

HBV-LPP integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2461

Orient

+

Integrated sequence

AGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCT| |TGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTAC

Chromosome

chr3

Cytoband

q28

Reference genome

Start

End

188468083/188750295 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-142-3p ; hsa-mir-758-5p ; hsa-mir-3190-3p ; hsa-mir-548aw ; hsa-mir-6079 ; hsa-mir-4762-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-4452 ; hsa-mir-376a-5p ; hsa-mir-3192-3p ; hsa-mir-4684-3p ; hsa-mir-656-5p ; hsa-mir-4502 ; hsa-mir-4680-3p ; hsa-mir-5187-3p ; hsa-mir-4427 ; hsa-mir-491-3p ; hsa-mir-7156-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4729 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-4752 ; hsa-mir-620 ; hsa-mir-3911 ; hsa-mir-1270 ; hsa-mir-7847-3p ; hsa-mir-4697-3p ; hsa-mir-4683 ; hsa-mir-4289 ; hsa-mir-4302 ; hsa-mir-6733-3p ; hsa-mir-574-5p ; hsa-mir-297 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-511-3p ; hsa-mir-6782-5p ; hsa-mir-3936 ; hsa-mir-6820-3p ; hsa-mir-3164 ; hsa-mir-4765 ; hsa-mir-1236-5p ; hsa-mir-3174 ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-627-3p ; hsa-mir-942-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6726-3p ; hsa-mir-4294 ; hsa-mir-130b-5p ; hsa-mir-6812-3p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-4793-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-15a-3p ; hsa-mir-6888-5p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-1265 ; hsa-mir-191-5p ; hsa-mir-2392 ; hsa-mir-4327 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4740-3p ; hsa-mir-4742-5p ; hsa-mir-5093 ; hsa-mir-5186 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-7846-3p ; hsa-mir-1827 ; hsa-mir-19a-5p ; hsa-mir-19b-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-2052 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4666a-3p ; hsa-mir-4709-3p ; hsa-mir-4722-5p ; hsa-mir-485-5p ; hsa-mir-665 ; hsa-mir-6746-5p ; hsa-mir-6771-5p ; hsa-mir-6808-5p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-7849-3p ; hsa-mir-940

Nearest miRNA

hsa-let-7g/Upstream/61429; hsa-mir-3137/Downstream/1079627;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/595729, chr3-CpG: 25/Downstream/197191

Upstream sequence

ttatggattctttattttttcttgatcaatcctattaaaactttatcaactttaagtctcaagcctcaatgttgttaatttttctccttttcattgttta

Downstream sequence

TAATATGATCATTGGAGAAATACTCATTCCTTTGCATATTGGTTTACTATCCAAgccaggtgtggtggttcacacttgtaattccagcactttgggaggc