VISDB Viral Integration Site DataBase

VIS ID

TVIS10007163

Fusion event

HBV-ATP13A3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1919

Orient

+

Integrated sequence

AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA| |TAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGG

Chromosome

chr3

Cytoband

q29

Reference genome

Start

End

194145073/194424344 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-590-3p ; hsa-mir-122-5p ; hsa-mir-103a-3p ; hsa-mir-98-5p ; hsa-mir-16-5p ; hsa-mir-150-5p ; hsa-mir-182-5p ; hsa-mir-340-5p ; hsa-mir-5692a ; hsa-mir-545-3p ; hsa-mir-3617-3p ; hsa-mir-3163 ; hsa-mir-34a-3p ; hsa-mir-551b-5p ; hsa-mir-4282 ; hsa-mir-455-5p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-6516-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-5009-3p ; hsa-mir-5002-5p ; hsa-mir-5586-3p ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-107 ; hsa-mir-4666a-3p ; hsa-mir-548c-3p ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p

Nearest miRNA

hsa-let-7g/Upstream/4594335; hsa-mir-3137/Downstream/710162;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/26085, chr3-CpG: 118/Downstream/62399

Upstream sequence

aggctgaggcaggaggatcaccttgaggtcaggagttttgagacccacttggccaacatagtgaaaccctgtccctactaaaaatacaaaaattagccgg

Downstream sequence

CCAAAAAGGGGGCAAAAAAAAGGAAAAATTACCAGTGAGATCAGATTGTAATcttacctgcacaaaatataaagtaataaaacttgccctacaaaccaac