VISDB Viral Integration Site DataBase

VIS ID

TVIS10007164

Fusion event

HBV-OSBPL10 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

249

Orient

+

Integrated sequence

GCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGT| |CTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTT

Chromosome

chr3

Cytoband

p23

Reference genome

Start

End

31924789/31883297 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-222-3p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-6499-3p ; hsa-mir-3135b ; hsa-mir-103b ; hsa-mir-5693 ; hsa-mir-4781-3p ; hsa-mir-143-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6748-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-3934-3p ; hsa-mir-2467-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-383-3p ; hsa-mir-3149 ; hsa-mir-668-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3121-5p ; hsa-mir-483-3p ; hsa-mir-129-5p ; hsa-mir-3152-5p ; hsa-mir-3667-3p ; hsa-mir-4774-3p ; hsa-mir-6734-3p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p

Nearest miRNA

hsa-mir-12127/Upstream/721510; hsa-let-7g/Downstream/622986;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/349507, chr3-CpG: 104/Downstream/97180

Upstream sequence

cgtgttgtaattgatacaatctggctcagtactatctgatatttcaggcaaccactgggggccttgcagaatatatcccgtggataaggagagaatactg

Downstream sequence

ggcacgatctcagctcactgcaacctccacttcccaggttcaagtgattttcctgcctcagcctccccaagtagctgggattacagacaccaccacgccc