Fusion event
HBV-PPP2R2C integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
ACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTC| |AGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACC
End
6478480/6476753 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-378d-1/Upstream/553425; hsa-mir-12113/Downstream/833697;
Nearest cancer related gene
Upstream sequence
aaccttctaatcgggttgattctaatccattccattacattcaagtctttccattccatgccattcctcttgtgttgtttccattccattgaattccatt
Downstream sequence
gctttcatttgcacaatgttttttttctgagaagcactcatgttatttatatatatgtaactgtaatttattcatttttcattgttgtgtaatattctat
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.