Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007181
Fusion event
HBV-AUTS2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
3119
Orient
+
Integrated sequence
CCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCA| |GGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
Start
End
69910431/70445445 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1183/Upstream/3331048; hsa-mir-10399/Downstream/862227;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/845394, chr7-CpG: 64/Downstream/150403
Upstream sequence
tggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatgaa
Downstream sequence
CACTAACTCCTAAAAATTCAAACATGGCGGTTTCTCAAGAAACATGGAACGAATAAAATTTGGGTCTACTAACAACTTAGATTGTACAGGCTCTTCTGAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.