Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007184
Fusion event
HBV-CSMD3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
331
Orient
+
Integrated sequence
CTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCA| |ATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCAT
Host Sequence
Chromosome
chr8
Cytoband
q23.3
Reference genome
End
113456790/112444561 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12123/Upstream/7960096; hsa-mir-10400/Downstream/198932;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2468718, chr8-CpG: 21/Downstream/988036
Upstream sequence
acgtacacagcagcatactcagaaaatactttgccatatttccattcaagtcacagagtggaacattcccattcatagagcaggtttgaaacactctttt
Downstream sequence
gaatgaatctcaaaaattttatgatagcaaaaacataaggcaaacaaaatagtgcatacagtaatatttcacttgtgtggcattcaggaaaacatcaaac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.