Basic Information
VIS ID
TVIS10007198
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
694
Orient
+
Integrated sequence
TGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTG| |TTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTT
Host Sequence
Chromosome
chr1
Cytoband
p11.1
Reference genome
End
121484558/121742760 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/4648032; hsa-mir-1182/Downstream/24107827;
Nearby gene
EMBP1(-170872) ;
Upstream sequence
aactttcatttagagagagcagatttgaaacactgtttttgtggtatttgcaagtggagatttcaagcgctttggggccaaaggcagaaaaggaaatatc
Downstream sequence
ttcgtataaaaactagacagaatcattctcagtaactgctctgtgatgtgtgcgttcaactctcagagtttaacttttcttttcattcagcagtttggaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate