Basic Information
VIS ID
TVIS10007234
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
900
Orient
+
Integrated sequence
GTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTT| |ATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAAT
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
95221/10517 (Hg38)
End
95221/10517 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Downstream/1649798;
Nearest TSS
ENST00000382841/Downstream/27585;
Nearest CpG islands
None/Target, None/Upstream, chr12-CpG: 104/Downstream/20272
Nearby gene
WASH8P(-3958) ; FAM138D(+52725) ;
Upstream sequence
acccgggcgggcgggccggctgagggtaccgccagggttagggttagggttagggttggggttggggttagggttagggttagggttagggttagggtag
Downstream sequence
ggttagggttagggttggggttggggttggggttagggttagggttagggttagggtagggttagggttagggttaggggttaggggttaggggttaggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate