Basic Information
VIS ID
TVIS10007250
Fusion event
HBV-chr18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
900
Orient
+
Integrated sequence
GTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTT| |ATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAAT
Host Sequence
Chromosome
chr18
Cytoband
p11.32
Reference genome
GRCh37/hg19
Start
10241/10241 (Hg38)
End
10241/10241 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Downstream/102015;
Nearest TSS
ENST00000575820/Downstream/862;
Nearest CpG islands
None/Target, None/Upstream, chr18-CpG: 67/Downstream/1467
Nearby gene
ROCK1P1(+98824) ;
Upstream sequence
aacccttaaccctaacccttaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccccaaccccaaccccaaccctaacccctaacccct
Downstream sequence
accctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaccctaaccctaccctaccctaaccctaaccctaaccctaacccttaacccta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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