Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007256
Fusion event
HBV-DDX11L2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
409
Orient
+
Integrated sequence
AATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCT| |TCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCAC
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
End
114359761/113602184 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/19088; hsa-mir-10b/Downstream/119106;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/17463, chr2-CpG: 61/Downstream/24828
Upstream sequence
agcaggcggcgtgccaccactatacagtaagcaagagggccctgcagtgccccggcgccagcagggggcgctggcgaccactgtaagcaagagagccctg
Downstream sequence
cgcctctctgcgccggcgccggcgcggcgcgcctctctgcgccggcgcggcgcggggtgcctttgcgacggcggagttgcgttctcctcagcacagaccc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.