Basic Information
VIS ID
TVIS10007266
Fusion event
HBV-LINC01829 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1818
Orient
+
Integrated sequence
GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
67411412/67184280 (Hg38)
End
67411412/67184280 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S
Target gene
LINC01829
Nearest miRNA
hsa-mir-1301/Upstream/825952; hsa-mir-10b/Downstream/1919402;
Nearest TSS
ENST00000437798/Upstream/6288; ENST00000445514/Downstream/29128;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/602008, chr2-CpG: 50/Downstream/212960
Upstream sequence
ATTTTTTTTTCTAACAGTAGTAATAACTGGCAAAAATTCATGTTGATTAGAATATGCCCAACTGCaaaaaaaaaaaaaaaaaaaaaaaaaaaCTTTTTCT
Downstream sequence
TTTCTTGCAGGAAGTGCACATGCATTTGTGTGCATGTTCAGTAGAGAAACATGAGAGTCTGGAAGTGCTGGAACAGGGAAAACTTGGATTTCCCAAGATT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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