Basic Information
VIS ID
TVIS10007267
Fusion event
HBV-chr2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
862
Orient
-
Integrated sequence
CCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGG| |TTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCT
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
End
83878716/83651592 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-1285-2/Upstream/3785009; hsa-mir-10b/Downstream/2132008;
Nearby gene
DHFRP3(-793823) ; FUNDC2P2(+639090) ;
Upstream sequence
GAACTCCCCAGTGGTAAATAAAATATATCATTCCCTTGGCCATCAAAATAGTTCTCATATAAAATTACAAGCATATATTCCAATAGGTGTTAGAAGGAAT
Downstream sequence
GGGCTTTCTATTAGAGAATAGTGGTTTTTAAAAGATAGACTGAGAACTTCTCAGATAAAAGCTAATTAGCCTTTGAAACATGCAGAACTGGGAATGGAAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate