Basic Information
VIS ID
TVIS10007274
Fusion event
HBV-chr20 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
900
Orient
+
Integrated sequence
GTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTT| |ATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAAT
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
62918533/64287180 (Hg38)
End
62918533/64287180 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-1/Upstream/210170;
Nearest TSS
ENST00000382410/Upstream/15698; ENST00000279067/Downstream/3205;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/16619, chr20-CpG: 92/Downstream/29115
Nearby gene
PCMTD2(-10954) ; LINC00266-1(+3205) ;
Upstream sequence
agggttaggggttaggggttagggttagggttagggtaagggtaagggttaggattaggggttagggttagggttagggttagggttagggttagggtag
Downstream sequence
ggttagggttagggttagggttaggggttaggggttagggttagggttagggtaagggtaagggttaggattaggggttagggttagggttagggttagg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate