Basic Information
VIS ID
TVIS10007291
Fusion event
HBV-chr3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2834
Orient
+
Integrated sequence
CAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGG| |AACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAA
Host Sequence
Chromosome
chr3
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
98412795/98693951 (Hg38)
End
98412795/98693951 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/2333912; hsa-mir-12124/Downstream/1270363;
Nearest TSS
ENST00000440867/Upstream/100228; ENST00000465004/Downstream/38285;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/36253, chr3-CpG: 50/Downstream/38491
Nearby gene
CPOX(-100340) ; ST3GAL6-AS1(+20382) ;
Upstream sequence
tggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatgaa
Downstream sequence
aggttcttaagatttaagagaaaggatgtCCATCAAGTGAAAGGCAAGGAGTGACTGAGTAGAAATATCCATTCCCTTTCCCCTCTCTTTAACCCATCAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate