VISDB Viral Integration Site DataBase

VIS ID

TVIS10007295

Fusion event

HBV-MGST2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1821

Orient

+

Integrated sequence

TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA

Chromosome

chr4

Cytoband

q31.1

Reference genome

Start

End

140630218/139709064 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-340-3p ; hsa-mir-106a-5p

Nearest miRNA

hsa-mir-12113/Upstream/14201757; hsa-mir-1305/Downstream/3634396;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/10438, chr4-CpG: 96/Downstream/25744

Upstream sequence

ctgattgcaaccaatcagatgtttgcacagtagtgtgacctttgtaacttcacttctcttctggttggcggctctctgcaaccaatcagactgattgccg

Downstream sequence

GAAAAAAtttttttttttttttttttttttttttttgagatggagtctcactctgtcgcccaggccggagtgcagtggtgcgatttctgctcattgcaag