Basic Information
VIS ID
TVIS10007300
Fusion event
HBV-MIR548AJ2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1635
Orient
-
Integrated sequence
CTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCA| |AATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGG
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
End
23372657/23371034 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/855649; hsa-mir-1243/Downstream/1149158;
Upstream sequence
ttcacactgaggaaactagtgattaggcaggctgggtaaattatctaagatctgaaatgatcaagtagaatttgaattcacatcttcctaacttcaaaac
Downstream sequence
taaaacttacaaagaagaatattttTTAATTATCTTTCAGGAATATTTAATCTCTGGGTACCACAAATCCTGTTCAACCTCggactttggggaggtaggt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate