VISDB Viral Integration Site DataBase

VIS ID

TVIS10007308

Fusion event

HBV-BMPR1B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1938

Orient

-

Integrated sequence

AATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACT| |GTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTG

Chromosome

chr4

Cytoband

q22.3

Reference genome

Start

End

95970566/95049415 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-let-7a-5p ; hsa-mir-22-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4705 ; hsa-mir-4668-3p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-12113/Upstream/7748832; hsa-mir-1243/Downstream/3947972;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/290757, chr4-CpG: 20/Downstream/498890

Upstream sequence

tggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatgaa

Downstream sequence

AAAGtttttttttttttttttttttttttttttttttttttttttttttttttttGCAGTTCATATATTCCAAACTCTGTAACCTATATTCAGAGTCCTg