Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007319
Fusion event
HBV-SPOCK1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2037
Orient
-
Integrated sequence
TGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCT| |GAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATC
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
End
136678646/137342957 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/1539882; hsa-mir-103a-1/Downstream/304615;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/985603, chr5-CpG: 134/Downstream/155370
Upstream sequence
atggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatga
Downstream sequence
CCAAAATGTAATGACTAATGCTAGATAAATGATCTGATGCCAGATCAAGTGTTAAACCAAAAGAACTGTATTCCCAAAGCAGGCTTTCAGGCATCAGAAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.