Basic Information
VIS ID
TVIS10007323
Fusion event
HBV-LOC105374873 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2018
Orient
+
Integrated sequence
ATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCG| |GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG
Host Sequence
Chromosome
chr6
Cytoband
p25.3
Reference genome
End
741275/741275 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Downstream/649039;
Nearby gene
EXOC2(-48134) ; LINC01622(+219966) ;
Upstream sequence
CTATTAACTTTTCTCAATAAAAATTATTAGAGAAggccgggtgttgtggctaacgcctgtcgtcccagcactttgggaggccgagacgggcggatcacga
Downstream sequence
cacctggctttgtttttccatttataaagcacagacagagtagttttaatataatttttaagcattctaggattttcagaatagtaaataatcactggct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate