Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007329
Fusion event
HBV-ADCY8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1828
Orient
+
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr8
Cytoband
q24.22
Reference genome
End
131924255/130912009 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1204/Upstream/903556; hsa-mir-10400/Downstream/2134472;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/467970, chr8-CpG: 207/Downstream/127994
Upstream sequence
ggaaacggtaatgtcttcaaagaaaatctagacagaaacattctcagaaacaccttcgtgatgtttgcaatcaagtcacagagttgaaccttccgtttca
Downstream sequence
tgttccttctttcctctctgggaccatggtgcttcctcaatctggaatgtccattacctctttcaatggaagagcttctactccatcttttagagtgaag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.