VISDB Viral Integration Site DataBase

VIS ID

TVIS10007332

Fusion event

HBV-HOOK3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1270

Orient

+

Integrated sequence

GTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCA| |TACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCG

Chromosome

chr8

Cytoband

p11.21

Reference genome

Start

End

42823576/42968433 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-615-3p ; hsa-mir-181a-3p ; hsa-mir-181a-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-302e ; hsa-mir-4662a-5p ; hsa-mir-6787-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-5692a ; hsa-mir-2681-5p ; hsa-mir-3529-3p ; hsa-mir-578 ; hsa-mir-3683 ; hsa-mir-1273c ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-3653-5p ; hsa-mir-6790-3p ; hsa-mir-6513-3p ; hsa-mir-1224-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-6844 ; hsa-mir-2052 ; hsa-mir-4508 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-4314 ; hsa-mir-7977 ; hsa-mir-6806-5p ; hsa-mir-3178 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4486 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-383-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-514a-5p ; hsa-mir-665 ; hsa-mir-5089-5p ; hsa-let-7e-3p ; hsa-let-7d-3p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-2115-5p ; hsa-mir-4305 ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-5586-5p ; hsa-mir-1273e ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-219b-3p ; hsa-mir-17-3p ; hsa-mir-1247-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-302f ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-27b-5p ; hsa-mir-556-5p ; hsa-mir-541-3p ; hsa-mir-1827 ; hsa-mir-25-5p ; hsa-mir-3664-3p ; hsa-mir-4327 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4649-3p ; hsa-mir-4695-5p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-6087 ; hsa-mir-6808-5p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-940 ; hsa-mir-4537 ; hsa-mir-510-3p ; hsa-mir-5585-5p ; hsa-mir-1273f ; hsa-mir-1289 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-134-3p ; hsa-mir-143-3p ; hsa-mir-3136-3p ; hsa-mir-3198 ; hsa-mir-3664-5p ; hsa-mir-4294 ; hsa-mir-4309 ; hsa-mir-452-5p ; hsa-mir-4534 ; hsa-mir-4639-3p ; hsa-mir-4676-3p ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-6514-5p ; hsa-mir-663b ; hsa-mir-6794-3p ; hsa-mir-7108-5p ; hsa-mir-7114-5p ; hsa-mir-7155-3p ; hsa-mir-8055 ; hsa-mir-8082 ; hsa-mir-892c-3p

Nearest miRNA

hsa-mir-124-1/Upstream/72158; hsa-mir-10400/Downstream/18746355;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/70444, chr8-CpG: 89/Downstream/87639

Upstream sequence

ctatggtgaaaaaggaaatatcttccaatgaaaacaagacagaagcattctgagaaacttatttgtgatgtgtgtcctcaactaacggacttgaaccttt

Downstream sequence

attcttctgccccagcctcctgagtagctggaactacagacgcatgctgccacacctggctaattttttgtattttggtaaagacagggtttcactgtgt