Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007350
Fusion event
HBV-PXDNL integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1942
Orient
-
Integrated sequence
ATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGG| |AGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCA
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
Start
End
52648078/51735518 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-124-1/Upstream/8839243; hsa-mir-10400/Downstream/9979270;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/325857, chr8-CpG: 108/Downstream/163092
Upstream sequence
aggattccctatttaataaatggtgctgggaaaactggctagccatatgtagaaagctgaaactggatcccttccttacaccttatacaaaaatcaattc
Downstream sequence
aaaaattgttttttttttttttttttttttttttttttttttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgggatctcggc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.