VISDB Viral Integration Site DataBase

VIS ID

TVIS10007364

Fusion event

HBV-PCDH11X integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1752

Orient

-

Integrated sequence

TACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA| |GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT

Chromosome

chrX

Cytoband

q21.31

Reference genome

Start

End

91142314/91887315 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-376a-2-5p ; hsa-mir-3935 ; hsa-mir-2115-3p ; hsa-mir-5694 ; hsa-mir-383-5p ; hsa-mir-432-3p ; hsa-mir-4775 ; hsa-mir-324-5p ; hsa-mir-1306-5p ; hsa-mir-590-3p

Nearest miRNA

hsa-let-7f-2/Upstream/5983608; hsa-mir-105-1/Downstream/3175826;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/105045, chrX-CpG: 20/Downstream/1786232

Upstream sequence

aaaacaattatgtgcacacatgtgcagttcctgagttcaagtaattctcctgcctcagcctcccgagcagctgggattacaggcacctgccaccatgccc

Downstream sequence

GTTTGTGTTTATTTTAAATATGACTTAGCTTCCTAGAATATTCAAAGATTCTGTGATAATACAAAGCTATATTTCTTGCATATAATTAGTATTTTTAGAA