VISDB Viral Integration Site DataBase

VIS ID

TVIS10007383

Fusion event

HBV-GNG12 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1662

Orient

-

Integrated sequence

TCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAG| |GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA

Chromosome

chr1

Cytoband

p31.3

Reference genome

Start

End

68191311/67725628 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-423-5p ; hsa-mir-186-5p ; hsa-mir-4279 ; hsa-mir-580-5p ; hsa-mir-584-5p ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-16-1-3p ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-144-3p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-5692a ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4477b ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-3973 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-4724-5p ; hsa-mir-6816-3p ; hsa-mir-8080 ; hsa-mir-548l ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4775 ; hsa-mir-590-3p ; hsa-mir-153-5p ; hsa-mir-3180-5p ; hsa-mir-6749-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-6756-3p ; hsa-mir-6832-3p ; hsa-mir-3127-3p ; hsa-mir-1182 ; hsa-mir-6814-5p ; hsa-mir-6870-3p ; hsa-mir-3065-5p ; hsa-mir-8063 ; hsa-mir-6504-3p ; hsa-mir-3529-3p ; hsa-mir-216a-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1097111; hsa-mir-11399/Downstream/457890;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/39041, chr1-CpG: 89/Downstream/107060

Upstream sequence

GGGAAAGGACTGATGATACAAGATGTTCCCAAGTCAACTTCTGACAGTTCTAACTCATTCCCTAAATTGATTAGAATTCTCTCTCTCTAAAAGCAAACTT

Downstream sequence

GATAACAGCTTCTTTTTAAAAGTGTTACTTGAGGGAAAACATGGGACAGAAATCAAAGCAAGCCATTTAAAGTCCAAACCCAATCAGCAACATCAATACA