VISDB Viral Integration Site DataBase

VIS ID

TVIS10007388

Fusion event

HBV-ERH integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1582

Orient

+

Integrated sequence

TCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGT| |GCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAA

Chromosome

chr14

Cytoband

q24.1

Reference genome

Start

End

69849110/69382393 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-92a-3p ; hsa-mir-4709-3p ; hsa-mir-1257 ; hsa-mir-340-5p ; hsa-mir-3185 ; hsa-mir-4635 ; hsa-mir-4501 ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-3154 ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-3935

Nearest miRNA

hsa-mir-208a/Upstream/1940463; hsa-mir-1185-1/Downstream/3134427;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/120717, chr14-CpG: 44/Downstream/15603

Upstream sequence

ttttCTGAAAACTCTTTGTCCATGCTTCCTAATTAAATAAGCTCTAAGCTAGTCTACTGCAAAATGTAGCAGAAGAGACTATAACATTTATATTAACACT

Downstream sequence

GGAAAATAACTTAAAAAGGAACAAAATTTCTCACAATTATCATATCTGGGTGGGACAGGCTTTGTTTATACCATTCCCCCCAACAAAAATCACTCTGGTT