Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007403
Fusion event
HBV-ALB integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
491
Orient
+
Integrated sequence
GTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGG| |ATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGA
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
Start
End
74285627/73419910 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12113/Upstream/7142982; hsa-mir-1243/Downstream/3153658;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/160497, chr4-CpG: 20/Downstream/200417
Upstream sequence
tggtagtttcttttgctgtgcagaagctctttagtttaattagatcccatttgtcaattttggcttttgttgccattgcttttggtgttttggacatgaa
Downstream sequence
AATATTTTGATCATGAAATCAAAACATTAATTTATTTAAACATTTACTTGAAATGTGGTGGTTTGTGATTTAGTTGATTTTATAGGCTAGTGGGAGAATT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.