Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10007407
Fusion event
HBV-SLC6A7 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1886
Orient
+
Integrated sequence
AGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCT| |TGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGA
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
End
149590176/150210613 (Hg38)
Orient
+
Location type
UTR3
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/477723; hsa-mir-103a-1/Downstream/1311474;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/20231, chr5-CpG: 48/Downstream/86802
Upstream sequence
aggattccctatttaataaatggtgctgggaaaactggctagccatatgtagaaagctgaaactggatcccttccttacaccttatacaaaaatcagttc
Downstream sequence
GGTAGGAAGGGTCACTGTGAGGGCCCAGGGCCCCTCTCTTCCCATCTCCCTTGTCCTGGTGGCCTTCAGTGTCTCTTCCAGTTCCAGGAGCTGCTGGGAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.