VISDB Viral Integration Site DataBase

VIS ID

TVIS10007408

Fusion event

HBV-SOBP integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1256

Orient

+

Integrated sequence

CCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCT| |CCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCC

Chromosome

chr6

Cytoband

q21

Reference genome

Start

End

107922031/107600827 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-324-5p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-302f ; hsa-mir-5187-3p ; hsa-mir-8081 ; hsa-mir-432-5p ; hsa-mir-487b-3p ; hsa-mir-513b-5p ; hsa-mir-4424 ; hsa-mir-15b-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-6757-3p ; hsa-mir-7849-3p ; hsa-mir-599 ; hsa-mir-584-5p ; hsa-mir-2052 ; hsa-mir-144-5p ; hsa-mir-6814-5p ; hsa-mir-758-5p ; hsa-mir-218-2-3p ; hsa-mir-4733-5p ; hsa-mir-8076 ; hsa-mir-3123

Nearest miRNA

hsa-mir-10398/Upstream/816607; hsa-mir-1202/Downstream/11468220;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/109822, chr6-CpG: 169/Downstream/33132

Upstream sequence

ACTGGAAAGGTCCGTCAGGTGGTTTATTTGCTTTCCAATAAACCAGCTTTATTAGCTTAGAGTTGAATTTTTTAGATTACAAAAAGTGATCTTggtagac

Downstream sequence

tgggtgcctactatgtgcagggcacAAAATCATTTTGGATGGGCATGAAATGAACTCGATTTTTACAGATTTCTACCCCTCATTTTTACAAGATCattat