VISDB Viral Integration Site DataBase

VIS ID

TVIS10007412

Fusion event

HBV-SH2D4A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

373

Orient

+

Integrated sequence

AATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATC| |GCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGT

Chromosome

chr8

Cytoband

p21.3

Reference genome

Start

End

19171900/19314389 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-8055 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4468 ; hsa-mir-873-3p ; hsa-mir-942-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-7113-3p ; hsa-mir-6832-3p ; hsa-mir-4461

Nearest miRNA

hsa-mir-124-1/Upstream/1632732; hsa-mir-10400/Downstream/2930577;

Nearest TSS

Nearest CpG islands

chr8-CpG: 100/Target, None/Upstream, None/Downstream

Upstream sequence

gaattttcaAGTCATCCTTTTAATATATTAATATACAATACATGAATAATTTATGTATTCATGCCACGAACAATTTCTTTCTTTAATTAAATTAAGGGGT

Downstream sequence

CCCCACGTGGGGTCTGGGAGCGCGCGGAGGCCAGTGCAGCGCCGCCTCCCTCGGGCTGCAGCGGCGGGGCTGGCCCAGACCCAGACCGGGTGCCCAGTGC