VISDB Viral Integration Site DataBase

VIS ID

TVIS10007421

Fusion event

HBV-RNF19B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

521

Orient

-

Integrated sequence

TATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCG| |GACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCC

Chromosome

chr1

Cytoband

p35.1

Reference genome

Start

End

33423267/32957666 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6780a-3p ; hsa-mir-146a-3p ; hsa-mir-3923 ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-6802-3p ; hsa-mir-411-5p ; hsa-mir-4662a-5p ; hsa-mir-3152-3p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-483-5p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-6836-3p ; hsa-mir-1251-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-2276-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-6736-3p ; hsa-mir-6890-3p ; hsa-mir-216a-5p ; hsa-mir-516a-5p ; hsa-mir-4279 ; hsa-mir-4444 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-122-3p ; hsa-mir-5698 ; hsa-mir-4430 ; hsa-mir-143-5p ; hsa-mir-3652 ; hsa-mir-6722-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-5693 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-640 ; hsa-mir-3663-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-5089-5p ; hsa-mir-6878-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-212-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-5001-3p ; hsa-mir-2355-5p ; hsa-mir-4772-3p ; hsa-mir-6752-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a

Nearest miRNA

hsa-mir-12136/Upstream/870659; hsa-mir-101-1/Downstream/374727;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/55945, chr1-CpG: 101/Downstream/6264

Upstream sequence

ctcacacctgtaatcccagcactttgggagggtgaggcgggtggctcgcttgaagtcaggaattcaagcccagcctggccaacatggtgaaaccctgttt

Downstream sequence

ctactaaaaatacaaacattagctggacattgtggcacatgcctgtaatcccagatacttgggaggctgaggcagaagaatcgcttgaacccgagaggca