VISDB Viral Integration Site DataBase

VIS ID

TVIS10007422

Fusion event

HBV-KANK4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1798

Orient

-

Integrated sequence

TGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTG| |GTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTG

Chromosome

chr1

Cytoband

p31.3

Reference genome

Start

End

62757364/62291692 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-510-3p ; hsa-mir-1290 ; hsa-mir-103a-2-5p ; hsa-mir-4738-3p ; hsa-mir-6884-3p ; hsa-mir-1207-3p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-448 ; hsa-mir-153-3p ; hsa-mir-3119 ; hsa-mir-6813-5p ; hsa-mir-6085 ; hsa-mir-129-5p ; hsa-mir-3936

Nearest miRNA

hsa-mir-12132/Upstream/212833; hsa-mir-101-1/Downstream/1035233;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/96418, chr1-CpG: 103/Downstream/26773

Upstream sequence

accAGGTACACCTAAtttttttttttggttattgagacagagtctctccctgtcacctaggctggagtgcaatgacgtgatctcagctcaatgcaacctc

Downstream sequence

cacctcccgggatcaagtgattctcctgccttagcctcccaagtagctgggattacaggtgtgcaccaccacgcctggctaatcttgtatttttagtaga